Maxillofacial Trauma TeamBiomedical Engineering for OMS← Main site

RESEARCH PROGRAM · CARLOS A. ANDREUCCI, DDS, MSc, PhD

Biomedical Engineering
in service of OMS.

A clinical-engineering program investigating how fixation, implant geometry, autogenous bone, biomaterials and physical forces can work together to improve Oral and Maxillofacial Surgery.

01 / CLINICAL FOUNDATION

Innovation began with restraint, not with more hardware.

Professor Gino Emilio Lasco believed that bone-fixation screws required caution and careful planning. In selected cases, his team prioritized normal function and a surgical technique adapted to the individual rather than rigid fixation. Resorbable sutures could maintain position without rigid hardware. Surgical steel remained indispensable. Plates and screws had their strongest indications in the mandible, where stability could be decisive.

As materials, manufacturing and biomedical engineering improved, fixation systems became more efficient mechanically and biologically. The clinical principle, however, remained unchanged: use the least intervention that can safely preserve function, anatomy and healing.

Technology should serve the biological objective. It should never replace clinical judgment.

02 / THE 2005 OBSERVATION

A 2 mm drill carried the clue.

During an implant procedure in 2005, Carlos A. Andreucci observed that a drill approximately 2 mm in diameter and 10 mm long repeatedly emerged with bone adhered to its cutting flutes. The observation raised a practical question: could an implant do more than occupy a prepared cavity?

After the operation, he modified a titanium implant model with a cylindrical diamond bur. That first physical alteration introduced the design logic that later became the Bioactive Kinetic Screw, or BKS.

Clinical observationBone remained in the drill flutesThe removed material was treated as useful information, not surgical waste.
Design questionCould the implant collect what it cuts?Geometry became part of the surgical and biological strategy.
Mechanical propositionCut, collect, compact and retainA dental implant evolved into a proposed multifunctional simple-machine platform.
Research programMeasure the mechanical advantageNumerical, experimental, material, biological and translational studies followed.

INTERACTIVE RESEARCH MODEL

Explore the Bioactive Kinetic Screw in three dimensions.

The interactive STL model presents the BKS geometry that developed from the 2005 clinical observation. Rotate and enlarge the device to examine its threads, cutting edges, transpassing hole and apex. These features support the proposed sequence of cutting, collecting, compacting and retaining autogenous bone.

Research modelThis model supports visual and engineering study of the BKS concept developed by Carlos A. Andreucci. It is presented for education and research, not as patient-specific clinical guidance.

Loading the BKS model...

01 Threads02 Cutting edges03 Transpassing hole04 Apex
Reference diagram identifying BKS threads, cutting edges, transpassing hole and apex
Labelled reference diagram corresponding to the interactive three-dimensional model.

03 / DOCTORAL FOUNDATION

Biomechanical Applications of a Novel Simple Machine

The initial studies culminated in a doctoral thesis approved at the University of Porto, Faculty of Engineering, within Mechanical Engineering and Biomedical Engineering. The work was supervised by Professor Renato Natal Jorge and Professor Elza M. M. Fonseca.

The thesis organized BKS as a platform for bone fixation, drilling, material collection, densification, graft transport and measurement, establishing the foundation for the subsequent publication program.

Access the doctoral thesis ↗
Institution
University of Porto, FEUP
Field
Biomedical Engineering and Mechanical Engineering
Researcher
Carlos Aurelio Andreucci
Supervision
Renato Natal Jorge and Elza M. M. Fonseca
Persistent record
hdl.handle.net/10216/158130

04 / RESEARCH ARCHITECTURE

One clinical question.
Six connected programs.

The program progresses from a measurable device mechanism to broader questions about living tissue, physical integration and clinical translation.

01

BKS mechanism and stability

Study simultaneous cutting, drilling, collection and compaction, together with insertion torque, removal torque, friction, pressure and early mechanical fixation.

02

Bone as an active material

Investigate retained autogenous particles, increased material density, immediate graft transport, remodeling and the transition from primary mechanics to biological integration.

03

Materials and bioactive surfaces

Compare titanium manufacturing routes, hierarchical micro and nanotopographies, anodization, additive manufacturing and infection-resistant or regenerative surface strategies.

04

Modeling and measurement

Combine finite element analysis, CFD-DEM, torque acquisition, compression and failure testing, microscopy, imaging and reproducible synthetic and biological models.

05

BPEM and functional living systems

Develop testable links among mechanical loading, piezoelectricity, electromagnetic interaction, vascular response, homeostasis, osseointegration and biocompatibility.

06

Translation for OMS

Convert engineering findings into safer fixation strategies, implant design, craniofacial reconstruction, education and clinically meaningful research questions.

05 / ACADEMIC DISCIPLINE

Separate what is published from what must still be tested.

PUBLISHED FOUNDATION

Mechanism and feasibility

Peer-reviewed work reports numerical models, prototyping, material densification, biotribology, bone collection, torque and stability, autogenous graft transport, sinus-lift concepts, mandibular osteotomy biomechanics, frictional cohesive force and bioactive surface development.

ACTIVE QUESTIONS

Mechanobiological integration

Current questions include vascularized bone ingrowth, internal osseointegration, interface load transfer, micromotion, flow and compaction, the transition from early mechanical stability to remodeling, and the role of physical fields in homeostasis.

NEXT VALIDATION

Independent and multicenter evidence

Priorities include standardized controls, full torque curves, FEA and CFD-DEM validation, microscopy, in vivo comparisons, long-term histology, fatigue testing, infection-resistant surfaces, reproducible datasets and regulatory planning.

CLINICAL TRANSLATION · PEER-REVIEWED CASE

When an implant complication revealed a systemic disease.

A 55-year-old man developed a left parasymphyseal mandibular fracture and osteomyelitis after an immediate mandibular implant protocol. The complication required more than fracture fixation: infection control, systemic bone assessment, mechanical stabilization and carefully adjusted rehabilitation had to work as one pathway.

DOI10.3390/osteology4010001Open the full article ↗inShare this case on LinkedIn
01CT views showing the parasymphyseal mandibular fracture, bone discontinuity and implants
Diagnose the full problemCT demonstrated fracture, loss of cortical continuity and the relationship to the implant region.
02Published operative views of debridement, fracture reduction and miniplate fixation
Control and stabilizeAfter infection control, necrotic tissue was removed and mandibular continuity restored with rigid internal fixation.
03Published views of the implant-supported overdenture and final occlusion
Rehabilitate the systemThree remaining implants supported an overdenture with repeated occlusal adjustment and one-year follow-up.
EmergencyFracture + osteomyelitis

Abscess drainage, antimicrobial therapy and close clinical monitoring created the conditions for definitive treatment.

Definitive repairDebridement + 2.0 miniplate

Bleeding bone margins, reduction and rigid fixation restored mandibular continuity after the infectious process was controlled.

Systemic findingPreviously undiagnosed osteoporosis

DEXA identified severe osteoporosis, with a reported femoral-neck T-score of -3.0, prompting specialist medical care.

OutcomeFunction restored at one year

The final prosthesis redistributed occlusal forces; follow-up recorded no pain, parafunction or recurrent abnormality.

WHY THIS CASE MATTERS

Implant planning cannot be separated from systemic bone health, infection risk and occlusal biomechanics. The successful result came from treating the patient as an integrated biological and mechanical system—not from addressing the fracture alone.

Calber Artur Andreucci, Murillo Martins and Carlos Aurelio Andreucci · Osteology 2024, 4, 1–10 · CC BY 4.0

06 / SELECTED PUBLICATIONS

Open the evidence in one click.

Selected publications defining the BKS, BPEM and OMS biomechanics research line. For the complete and continuously updated record, use ORCID.

View complete ORCID record ↗
2026Bioactive surfaces

Hierarchical Micro/Nanostructured Anodized Surface for a 3D-Printed Bioactive Kinetic Screw

Applied Sciences

Open publication ↗
2025Mechanical advantage

Frictional Cohesive Force and Multifunctional Simple Machine for Advanced Engineering and Biomedical Applications

Applied Sciences

Open publication ↗
2024Living systems

Biopiezoelectromagnetic and Mechanical Effect

Proceedings of the IMechE, Part L

Open publication ↗
2024OMS biomechanics

Biomechanics of a Novel 3D Mandibular Osteotomy Design

Designs

Open publication ↗
2024Clinical translation

Mandibular Fracture following Dental Implant Protocol: Clinical Report and One-Year Follow-Up

Osteology

Open publication ↗
2023Primary stability

Static in Bone Implants: Standard Steady-State Torque and Primary Stability in a Bioactive Kinetic Screw

Journal of the Brazilian Society of Mechanical Sciences and Engineering

Open publication ↗
2023Bone collection

A New Collector Device for the Immediate Use of Particulate Autogenous Bone Grafts

Applied Sciences

Open publication ↗
2023Sinus augmentation

A New Simplified Autogenous Sinus Lift Technique

Bioengineering

Open publication ↗
2023Autogenous grafting

Immediate Autogenous Bone Transplantation Using a Novel Kinetic Bioactive Screw 3D Design as a Dental Implant

BioMedInformatics

Open publication ↗
2023Biotribology

Bio-lubricant Properties Analysis of Drilling an Innovative Design of Bioactive Kinetic Screw into Bone

Designs

Open publication ↗
2022Additive manufacturing

3D Printing as an Efficient Way to Prototype and Develop Dental Implants

BioMedInformatics

Open publication ↗
2022Material densification

Increased Material Density within a New Biomechanism

Mathematical and Computational Applications

Open publication ↗
2022Numerical model

Proposal for a New Bioactive Kinetic Screw in an Implant, Using a Numerical Model

Applied Sciences

Open publication ↗

07 / INTERNATIONAL RESEARCH NETWORK

Bring a method.
Bring a clinical question.
Build the evidence together.

The program welcomes serious collaborators who can strengthen experimental rigor, independent validation and translation to patient care.

Propose a collaboration

ACADEMIC AFFILIATIONS AND COOPERATION

American International UniversityBiomedical Engineering Department, School of Engineering and Computing, Saad Al Abdullah, Block 3, Al Jahra 91100, Kuwait
ISEP, Polytechnic of PortoMechanical Engineering Department, ISEP, School of Engineering, Rua Dr. António Bernardino de Almeida 431, 4200-072 Porto, Portugal
Federal University of São Carlos, UFSCarDepartment of Physics, Chemistry and Mathematics, Sorocaba 18052-780, Brazil
Politecnico di MilanoScientific exchange and cooperation in biomaterials, implant engineering and additive manufacturing
University of BirminghamResearch development in biomaterials, bioactive surfaces and translational implant science
AO FoundationScientific and innovation network for musculoskeletal research and responsible translation
M4M SwissTechnology and manufacturing collaboration supporting advanced implant development

Institutional names indicate author affiliations, scientific cooperation or project participation. They do not necessarily represent formal institutional endorsement of the Maxillofacial Trauma Team.